Muchikamu chechitatu chekuedza, Tirzepatide yakaratidza migumisiro inokurudzira mukurapa kwechirwere cheshuga 2.Mushonga wacho wakawanikwa uchideredza zvakanyanya mazinga ehuga uye kukurudzira kuora muviri kune varwere vane chirwere.
Tirzepatide jekiseni kamwe chete pasvondo rinoshanda nekunanga glucagon-like peptide-1 (GLP-1) uye glucose-inotsamira insulinotropic polypeptide (GIP) receptors.Aya ma receptors anoita basa rakakosha mukudzora mazinga eshuga yeropa uye kukurudzira kugadzirwa kwe insulin.
Muedzo, wakatungamirirwa naEli Lilly neKambani, wakanyoresa vanhu vanopfuura 1,800 vane chirwere cheshuga chechipiri avo vakanga vasingatore insulini kana kutora chirwere chakagadzikana che insulini.Vatori vechikamu vakapihwa zvisina tsarukano kuti vagamuchire majekiseni evhiki nevhiki eTirzepatide kana placebo.
Pakupera kwekuyedzwa kwemavhiki makumi mana, vaongorori vakawana kuti varwere vakagamuchira Tirzepatide vaive neshuga yakanyanya kuderera kupfuura avo vakagamuchira placebo.Paavhareji, vatori vechikamu vakabatwa neTirzepatide vakawana kuderedzwa kwe2.5 muzana muhemoglobin A1c (HbA1c) mazinga, zvichienzaniswa ne1.1 muzana kuderedzwa muboka re placebo.
Mukuwedzera, varwere vanogamuchira Tirzepatide vakawanawo kurasikirwa kukuru.Paavhareji, vakarasikirwa ne11.3 muzana yehuremu hwemuviri wavo, zvichienzaniswa ne1.8 muzana yeboka re placebo.
Mhedzisiro yemuyedzo iyi inonyanya kukosha nekuda kwekuwanda kwechirwere cheshuga cherudzi rwechipiri pasi rose.Sekureva kweWorld Health Organisation, huwandu hwevanhu vakuru vanorarama nechirwere cheshuga hwakawedzera zvakapetwa kana kubva muna 1980, uye vanhu vakuru vanosvika 422 miriyoni vakabatwa muna 2014.
"Kutarisira chirwere cheshuga 2 kunogona kuva dambudziko kune vanhu vakawanda, uye nzira itsva dzokurapa dzinogamuchirwa nguva dzose," akadaro Dr. Juan Frias, muongorori anotungamirira pakudzidza."Migumisiro yechidzidzo ichi inoratidza kuti Tirzepatide inogona kupa sarudzo itsva inovimbisa kune varwere vane chirwere cheshuga chechipiri vari kunetseka kugadzirisa mazinga avo eshuga."
Kunyangwe zvimwe zvidzidzo zvichidikanwa kuongorora kuchengetedzeka kwenguva refu uye kushanda kweTirzepatide, zvinokurudzira zvemushonga uyu muyedzo yechikamu chechitatu chiratidzo chakanaka kune vanhu vane Type 2 chirwere cheshuga.Kana yakabvumidzwa nemasangano anodzora, Tirzepatide inogona kupa nyowani inoshanda yekurapa sarudzo yekudzora chirwere uye kugadzirisa hupenyu hwevarwere.
Nguva yekutumira: Jun-03-2023