Chidzidzo chitsva chinoona kuti mushonga semaglutide unogona kubatsira vanhu vane Type 2 chirwere cheshuga kuderedza uremu uye kuichengeta kure-refu.
Semaglutide ndeye kamwe-vhiki jekiseni mushonga uyo wakatenderwa neFDA kurapa mhando 2 chirwere cheshuga.Mushonga unoshanda nekukurudzira kusunungurwa kwe insulini mukupindura kune zvokudya, izvo zvinobatsira kugadzirisa mazinga ehuga.Mukuwedzera, semaglutide inoderedzawo kudya nekuita pane satiety centre yeuropi.
Chidzidzo chacho, chinotungamirirwa nevatsvakurudzi veYunivhesiti yeCopenhagen, vakatsvaga vanhu 1,961 vane chirwere cheshuga chechipiri uye body mass index (BMI) ye30 kana kupfuura.Vatori vechikamu vakagoverwa kuti vagamuchire majekiseni evhiki nevhiki eemaglutide kana placebo.Vose vatori vechikamu vakagamuchirawo mazano emararamiro uye vakakurudzirwa kutevera kudya kwe-calorie uye kuwedzera basa rekuita muviri.
Mushure memavhiki e68, vatsvakurudzi vakawana kuti varwere vanobatwa ne semaglutide vakanga varasikirwa nevhareji ye14.9 muzana yehuremu hwemuviri wavo, zvichienzaniswa ne2.4 muzana muboka re placebo.Mukuwedzera, vanopfuura 80 muzana yevarwere vanobatwa ne semaglutide vakarasikirwa zvishoma ne5 muzana yehuremu hwemuviri wavo, zvichienzaniswa ne34 muzana yevarwere vanobatwa ne placebo.Kurasikirwa kwehuremu kunowanikwa ne semaglutide kwakachengetwa kusvika kumakore maviri.
Chidzidzo chacho chakawanawo kuti varwere vanobatwa ne semaglutide vakawana kuvandudzwa kukuru mukutonga shuga yeropa, ropa uye cholesterol mazinga, izvo zvose zviri mungozi yehutano hwemwoyo.
Zvigumisiro zvechidzidzo ichi zvinoratidza kuti semaglutide inogona kuva nzira yekurapa inoshanda kune vanhu vane chirwere cheshuga 2 vari kunetseka kuderedza uremu.Mushonga uyu kamwe-vhiki nevhiki dosing chirongwa zvakare inoita kuti ive sarudzo iri nyore kune varwere vanogona kunetseka kutevedzera zuva nezuva dosing regimen.
Kurasikirwa kwehuremu mabhenefiti e semaglutide anogona zvakare kuve neakawanda mhedzisiro yekurapa kufutisa, njodzi huru yerudzi rwe 2 chirwere cheshuga, chirwere chemoyo uye zvimwe zvirwere zvisingaperi.Kufutisa kunokanganisa vanopfuura chikamu chimwe muzvitatu chevakuru muUnited States, uye kurapwa kunoshanda kunodiwa kugadzirisa dambudziko iri riri kukura rehutano hweveruzhinji.
Kakawanda, zvigumisiro zvekudzidza zvinoratidza kuti semaglutide inogona kuva yakakosha kuwedzera kune nzira dzokurapa dzinowanikwa kune varwere vane chirwere cheshuga chechipiri uye kuneta.Nekudaro, sekunge chero mushonga, zvakakosha kuti varwere vakurukure njodzi dzinogona kuitika uye mabhenefiti nevanopa hutano uye nekunyatsotevera yakatemwa dosing uye yekutarisa mirairo.
Nguva yekutumira: Jun-03-2019